Author

Balamurugan Dhayalan

Indiana University IndianapolisORCID 0000-0001-6002-1207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Michael Aaron WeissiD· 2 shared Norman MetanisiD· 2 shared Orit Weil‐Ktorza· 2 shared Yen‐Shan CheniD· 2 shared Yanwu YangiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBiochemistry

Michael Aaron WeissORCID

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2 papers

Recent·Most cited

BiochemistryChemBioChemPeer-reviewedDec 27, 2023

Se-Glargine I. Chemical Synthesis of a Basal Insulin Analog Stabilized by an Internal Diselenide Bridge

Orit Weil‐Ktorza, Balamurugan Dhayalan, Yen‐Shan Chen…·Norman Metanis

This paper describes the chemical synthesis of a basal insulin analog with an internal diselenide bridge, demonstrating improved stability and potential therapeutic applications.

11 citations

protein structureexperimental assay

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BiochemistrybioRxivPreprintJun 24, 2023

Se-Glargine II. Native Function of a Basal Insulin Analog Stabilized by an Internal Diselenide Bridge

Yen‐Shan Chen, Balamurugan Dhayalan, Yanwu Yang…·Michael Aaron Weiss

This paper describes an insulin analog with an internal diselenide bridge that maintains native function and stability, potentially improving insulin shelf life and accessibility.

3 citations

humanproteomics

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