Bhavani Shankar Sahu

This study identifies the role of AP-3 complex in regulating dense core vesicle (DCV) function, revealing its impact on exocytosis, positioning, and trans-Golgi budding, and identifies Dlk1 as a novel DCV cargo.

This study shows that lipid membrane interfaces drive α-synuclein condensation and fibrillation at low concentrations, revealing a mechanism for its propagation in neurodegeneration.

This study shows PDK4 links ERUPR and mitoUPR, affecting mitochondrial integrity in aging and neurodegeneration.

This study shows that Sida cordifolia extract reduces mutant huntingtin protein aggregation in Huntington's disease models, improving motility and lifespan in worms and reducing ER stress in cells.

This study shows that downregulating Pten improves HD symptoms in fly and cell models by reducing aggregates and apoptosis.