Author

Jonathan H. Chen

Broad InstituteORCID 0000-0001-6074-9302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Nir HacoheniD· 3 shared Adam L. Essene· 1 shared Alex K. ShalekiD· 1 shared Alexander SturmiD· 1 shared Alexandra–Chloé VillaniiD· 1 shared Alkes L. PriceiD· 1 shared Anat O Stemmer-RachamimoviD· 1 shared Andrea GannaiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersGenomics

Nir HacohenORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintMar 7, 2024

Integrating spatial transcriptomics count data with Crescendo improves visualization and detection of spatial gene patterns

Nghia Millard, Jonathan H. Chen, Mukta G. Palshikar…·Ilya Korsunsky

1 citation

mousespatial transcriptomics

𝕏 PostBluesky

GenomicsCell Reports MedicinePeer-reviewedFeb 1, 2022

Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma

Samuel S. Freeman, Moshe Sade-Feldman, Jaegil Kim…·Nir Hacohen

The paper develops DNA- and RNA-based models combining immune and tumor features to predict outcomes of checkpoint inhibition in melanoma.

38 citations

humanwhole-exome sequencing

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GenomicsbioRxivPreprintFeb 25, 2021

A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2

Toni Marie Delorey, Carly G.K. Ziegler, Graham Heimberg…·Alexandra–Chloé Villani

This study creates a single-cell and spatial atlas of autopsy tissues from COVID-19 patients, revealing altered cellular responses and potential therapeutic targets.

40 citations

𝕏 PostBluesky