Cell BiologybioRxivPreprint
YAP dysregulation triggers hypertrophy by CCN2 secretion and TGFβ uptake in human pluripotent stem cell-derived cardiomyocytes
Orlando Chirikian, Mohamed A. Faynus, Markus W. Merk…·Beth L. Pruitt
This study shows that YAP overactivation in HCM mutant cardiomyocytes drives hypertrophy via CCN2 secretion and TGFβ uptake.
1 citation