Lena G. Gerwick

The paper characterizes the structure of a putative terminal amidation domain in natural product biosynthesis and identifies its potential catalytic role.

This paper identifies hectoramide B, a new linear depsipeptide from Moorena producens JHB, through co-culture with Candida albicans and genome-based biosynthesis analysis.

NPOmix connects mass spectrometry fragmentation data to biosynthetic gene clusters using a k-nearest neighbor classifier, improving metabolite discovery and structure prediction.

This paper develops genetic tools for heterologous expression of biosynthetic gene clusters in cyanobacteria, enabling high-titer production of cryptomaldamide in Anabaena.

MetaRiPPquest identifies RiPPs by combining genome/metagenome mining with mass spectrometry analysis, discovering 5 novel natural products from 6 datasets.