Hillary Elrick

SAVANA improves detection of somatic structural variants and copy number aberrations in cancer using long-read sequencing with higher sensitivity and specificity than existing tools.

This study identifies chromothripsis and a novel LTA chromothripsis mechanism driving genome complexity and evolution in osteosarcoma, with prognostic implications for high-grade tumors.

The paper analyzes 3,313 genetically engineered mouse lines to identify gene essentiality as the main factor affecting Cas9-based genome editing success.

CReSCENT provides a web-based toolkit for analyzing scRNA-seq data in cancer research, offering preconfigured pipelines and user-editable workflows for non-experts.

FORCAST is a software pipeline that integrates existing tools to design, evaluate, and store Cas-mediated mutagenesis experiments.