Andreas Schedlbauer

This study identifies the binding site of the antibiotic GE81112 in the ribosomal mRNA channel using cryoEM, showing it acts allosterically to inhibit translation initiation.

This study thermodynamically stabilizes human frataxin using computational methods, improving its stability and resistance to proteolysis without compromising function.

This study determines the structure of KBP-7072 bound to the 30S ribosomal subunit, showing it inhibits protein synthesis by binding to the primary tetracycline site and interacting uniquely with the subunit.