Amber Riaz-Bradley

The paper shows that intrinsic transcription termination via RNA hairpins functions efficiently in the thermophile Thermus aquaticus at high temperatures, with RNA polymerase promoting hairpin formation.

This study presents the structure of Si3, a unique insertion in cyanobacterial RNA polymerase, and shows it does not affect catalytic activity despite large motion.

The paper investigates how cyanobacteria compensate for lacking transcription proofreading factors by showing their RNA polymerase actively compensates through structural changes, with trade-offs in regulatory pausing.