Damian J. Krysan

This study identifies genetic determinants of CO2 tolerance in Cryptococcus neoformans through a genome-wide screen and shows it involves metabolic remodeling and stress response pathways.

This study investigates how azole and phenothiazine drugs activate the C. glabrata Pdr1 pathway, showing distinct kinetics and mechanisms of CDR1 induction.

The paper identifies mefloquine analogs with broad-spectrum antifungal activity, effective against Candida auris in vivo.

This paper compares the temporal dynamics of morphogenesis and gene expression during C. albicans filamentation in vitro and in vivo, identifying key differences in metabolic gene expression and hyphae-to-yeast transition rates.

This study shows that the function of the C. albicans transcriptional repressor NRG1 varies by strain, affecting filamentation and virulence in different contexts.

This study compares gene expression dynamics during in vitro and in vivo filamentation in Candida albicans, finding prolonged gene expression and adaptation in vivo.