Author
The University of MelbourneORCID 0000-0001-6341-4364Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Charles W.E. Tomlinson, Stefano Elli, Morgan E Batiste-Simms…·Alan Cartmell
This paper investigates why aryl sulfatases are inhibited by sulfamate warheads while carbohydrate sulfatases are not, using structural and computational analyses.
Jennifer Ross, Moescha Hoopman, Florian Küllmer…·Elisabeth C. Lowe
The paper identifies functional and structural differences among three GH172 arabinofuranosidases from Dysgonomonas gadei using synthetic substrates, covalent inhibitors, and structural analysis.
Conor J. Crawford, Charles W.E. Tomlinson, Christian Gunawan…·Alan Cartmell
The paper shows arylsulfamates inhibit Bacteroides growth on sulfated glycans via a lipid kinase, not carbohydrate sulfatases, and identifies resistance mechanisms.
Aaron Franklin, Vivian Carolina Salgueiro, Abigail J. Layton…·Patrick Joseph Moynihan
This study identifies LamH, a glycoside hydrolase that cleaves -1,6-mannoside linkages in LAM/LM, enabling their export to the capsule and promoting bacterial growth.