Patrick Joseph Moynihan

This study identifies adhesin proteins in Nanosynbacteria that recognize specific host cell wall polysaccharides for recognition and attachment.

This study identifies AnkA as a bacterial effector that directly targets the WAVE Regulatory Complex and actin cytoskeleton, using molecular mimicry to subvert host cell functions during infection.

This study uses chemical genomics to identify gene-phenotype relationships in Vibrio cholerae by screening 104 stress conditions across 3,026 single-gene mutants, revealing 1,518 significant growth phenotypes including 88 unannotated genes.

The paper identifies functional and structural differences among three GH172 arabinofuranosidases from Dysgonomonas gadei using synthetic substrates, covalent inhibitors, and structural analysis.

The paper identifies a type VII-secreted toxin in mycobacteria that enables inter-bacterial competition by targeting arabinogalactan.

ChemGenXplore provides an interactive web tool for visualizing and analyzing chemical genomic data, enabling users to explore pre-implemented and uploaded datasets with various analytical features.

This study identifies lipoproteins LpqZ and FecB as essential for mycobacterial cell envelope biogenesis through interactions with enzymes involved in glycoconjugate synthesis.

This study identifies LamH, a glycoside hydrolase that cleaves -1,6-mannoside linkages in LAM/LM, enabling their export to the capsule and promoting bacterial growth.