Author

Peter T. McHale

University of UtahORCID 0000-0001-6452-1786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aaron R. QuinlaniD· 1 shared Michael E. GoldbergiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperGenomics

Aaron R. QuinlanORCID

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintJan 28, 2026

The performance of genetic-constraint metrics varies significantly across the human noncoding genome

Peter T. McHale, Michael E. Goldberg, Aaron R. Quinlan

The paper evaluates genetic-constraint metrics across the human noncoding genome, identifying biases and signal-to-noise issues, and proposes improvements for better interpretability.

1 citation

humanDNA methylation

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