Erik M. McIntire

The paper identifies genetic variants associated with cardiotoxic responses to chemotherapeutic drugs using single-cell RNA-seq and eQTL analysis.

The paper identifies that X chromosome dosage influences aneuploidy development in mouse embryonic stem cells, with XO and XY lines showing higher aneuploidy rates than XX lines.

The paper analyzes genetic changes in human pluripotent stem cells under different culture conditions and identifies a link between feeder-free culture and increased chromosome 1q gains.

This paper develops a guided differentiation protocol to generate cardiac cell aggregates (cardiac HDCs) from iPSCs, enabling the study of cardiac cell diversity through single-cell RNA-sequencing.