Author

Mark John Girasol

University of the Philippines ManilaORCID 0000-0001-6524-4952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Catarina A. MarquesiD· 2 shared Dario BeraldiiD· 2 shared Emma M. BriggsiD· 2 shared Leandro LemgruberiD· 2 shared Richard BurchmoreiD· 2 shared Richard McCullochiD· 2 shared Craig T. LapsleyiD· 1 shared Jeziel D. DamascenoiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMicrobiology

Catarina A. MarquesORCID

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2 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedNov 21, 2023

RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei

Mark John Girasol, Marija Krasiļņikova, Catarina A. Marques…·Richard McCulloch

This study shows RAD51 interacts with RNA-DNA hybrids and repairs DNA breaks at the transcribed VSG in T. brucei, linking RNA-DNA hybrids to antigenic variation.

26 citations

DNA methylationwhole-genome sequencing

𝕏 PostBluesky

MicrobiologyNucleic Acids ResearchPeer-reviewedSep 20, 2023

Immunoprecipitation of RNA-DNA hybrid interacting proteins in Trypanosoma brucei reveals conserved and novel activities, including in host immune evasion by antigenic variation

Mark John Girasol, Emma M. Briggs, Catarina A. Marques…·Richard McCulloch

The paper identifies 602 RNA-DNA hybrid interactors in Trypanosoma brucei using immunoprecipitation and mass spectrometry, revealing conserved and novel functions in DNA repair and immune evasion.

8 citations

humanproteomics

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