Florent Allagnat

SAAR improves exercise capacity in mice by enhancing fat oxidation and substrate availability through VEGF signaling and CD36-dependent fatty acid transport.

This study shows that sodium thiosulfate (STS), a hydrogen sulfide donor, reduces inflammation but worsens abdominal aortic aneurysm (AAA) progression by promoting smooth muscle cell apoptosis and ECM breakdown in mice.

This study develops an ex vivo human saphenous vein culture model to study intimal hyperplasia, revealing features like endothelial dysfunction, VSMC dedifferentiation, and osteochondrogenic differentiation.

This study identifies impaired glycolysis in aged endothelial cells as a factor limiting neovascularization during tissue ischemia.