Ferhat Alkan

The paper shows EWSR1::FLI1 fusion drives the production of cancer-specific neoproteins in Ewing sarcoma, revealing a reversible dark proteome with therapeutic potential.

The paper shows that mitochondrial damage can induce therapy-induced senescence in GBM cells through a ROS-cGAS-STING-SASP cascade, outperforming single or dual pathway inhibitors.

The paper identifies an 'alert-state' ribosome subpopulation (ASRs) that regulates cytokine-mediated processes by preferentially translating key mRNAs involved in immune responses.

The paper shows RNA dicing produces an oncogenic JAK1 isoform, affecting cell proliferation and tumorigenesis, and highlights its therapeutic implications.

Ribo-ODDR improves rRNA depletion in Ribo-seq by designing experiment-specific oligos, increasing sequencing depth and information yield.

The paper introduces BSGatlas, an enhanced genome annotation resource for Bacillus subtilis that integrates multiple sources to improve ncRNA and transcript annotations.