Pharmacology & ToxicologybioRxivPreprint
Single-Shot Design of a Cyclic Peptide Inhibitor of HIV-1 Membrane Fusion with EvoBind
Diandra Daumiller, Federica Giammarino, Qiuzhen Li…·Patrick Bryant
This paper introduces EvoBind, an AI method to design cyclic peptides that inhibit HIV-1 membrane fusion, demonstrating potent inhibition of two HIV-1 strains with no toxicity.
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