Cancer BiologybioRxivPreprint
Missense mutations in the calcium-activated chloride channel TMEM16A promote tumor growth by activating oncogenic signaling in Human Cancer.
Silvia Cruz‐Rangel, Jose Juan De Jesus-Perez, Avani Gopalkrishnan…·Duvvuri Umamaheswar
This paper investigates TMEM16A missense mutations in cancer, finding they promote tumor growth through altered signaling, independent of chloride flux.
1 citation