Virginia Vanni

The paper integrates single cell transcriptomics and chromatin accessibility data to uncover the regulatory logic of planarian stem cell differentiation, validating predictions with TF knockdown experiments.

This study investigates age-related changes in germline stem cells (GSCs) in the protochordate Botryllus schlosseri using single-cell RNA sequencing and transplantation assays, revealing that GSCs, not gametes, drive reproductive aging.

This study uses scRNA-seq to investigate cell type allometry in planarians, finding that gut basal cells respond most to size changes.

The paper identifies a new permanent stem cell niche in the ampullae of Botryllus schlosseri that contributes to asexual reproduction and regeneration.