Sebastian Gehlert

This study shows miR-1 regulates metabolic flexibility in skeletal muscle by controlling pyruvate metabolism, with loss of miR-1 causing metabolic inflexibility and reduced endurance.

This study shows acute exercise increases kynurenine pathway metabolites and activates the AHR in human PBMCs, linking exercise to immune modulation via this pathway.

This study shows that muscle hypertrophy involves cancer-like metabolic reprogramming, with PHGDH playing a key role in regulating myotube size through glycolytic pathways.