Aubrey R. Odom-Mabey

This study generates 50 complete Mtb genomes, identifies core and accessory gene clusters, and proposes a new pangenome reference resource to improve TB research.

MetaScope improves species-level classification of microbial communities using 16S rRNA data, achieving higher accuracy than existing tools like QIIME2 and DADA2.

The paper analyzes nasopharyngeal microbiome patterns in Zambian infants to identify differences between those who develop fatal acute febrile illness and healthy controls.

This study compares gene set scoring methods with original models for TB gene signatures, finding that gene set scoring can achieve equivalent or better performance than original models.

The paper evaluates taxonomic classification accuracy of 16S amplicon sequencing data using different pipelines and reference databases, finding that whole-genome tools outperform 16S-specific ones.