Author

David M. Murdoch

Duke UniversityORCID 0000-0001-7201-7950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

David M. MargolisiD· 3 shared Edward P. BrowneiD· 3 shared A. D. Cooper-VolkheimeriD· 2 shared Cynthia D RudiniD· 2 shared Lesia SemenovaiD· 2 shared Yingfan Wang· 2 shared Alton S. BarbehenniD· 1 shared Christopher D. Pilcher· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMicrobiology

David M. MargolisORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologyJournal of Cannabis ResearchPeer-reviewedMar 5, 2026

Single cell multiomic analysis of the impact of Delta-9-tetrahydrocannabinol on HIV infected CD4 T cells

Manickam Ashokkumar, Renee Y Ge, Alicia D. Volkheimer…·Edward P. Browne

This study investigates how THC affects HIV-infected CD4 T cells using single-cell multiomic analysis, finding no effect on HIV reactivation but altered gene expression and chromatin accessibility.

DOI 10.1186/s42238-026-00412-0

humanscRNA-seq

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MicrobiologybioRxivPreprintFeb 14, 2025

NF-κB dependent gene expression and plasma IL-1β, TNFα and GCSF drive transcriptomic diversity and CD4:CD8 ratio in people with HIV on ART.

Yingfan Wang, Germán G. Gornalusse, David A. Siegel…·Edward P. Browne

This study identifies transcriptomic clusters in HIV patients on ART linked to immune recovery and inflammation markers, revealing novel subgroups with distinct immunological profiles.

DOI 10.1101/2025.02.14.638232

humanbulk RNA-seq

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MicrobiologyeLifePeer-reviewedMar 23, 2024

Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.

Lesia Semenova, Yingfan Wang, Shane D. Falcinelli…·Edward P. Browne

The paper uses machine learning to analyze HIV reservoir and immunology data to identify immune signatures associated with total and intact HIV DNA levels during ART.

6 citations

humanbulk RNA-seq

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