Author

Lesia Semenova

Duke UniversityORCID 0000-0002-7742-3955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Cynthia D RudiniD· 2 shared David M. MargolisiD· 2 shared David M. MurdochiD· 2 shared Edward P. BrowneiD· 2 shared Yingfan Wang· 2 shared A. D. Cooper-VolkheimeriD· 1 shared Alton S. BarbehenniD· 1 shared Christopher D. Pilcher· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMicrobiology

Cynthia D RudinORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintFeb 14, 2025

NF-κB dependent gene expression and plasma IL-1β, TNFα and GCSF drive transcriptomic diversity and CD4:CD8 ratio in people with HIV on ART.

Yingfan Wang, Germán G. Gornalusse, David A. Siegel…·Edward P. Browne

This study identifies transcriptomic clusters in HIV patients on ART linked to immune recovery and inflammation markers, revealing novel subgroups with distinct immunological profiles.

DOI 10.1101/2025.02.14.638232

humanbulk RNA-seq

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MicrobiologyeLifePeer-reviewedMar 23, 2024

Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.

Lesia Semenova, Yingfan Wang, Shane D. Falcinelli…·Edward P. Browne

The paper uses machine learning to analyze HIV reservoir and immunology data to identify immune signatures associated with total and intact HIV DNA levels during ART.

6 citations

humanbulk RNA-seq

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