Marek Vrbacký

This study uses complexome profiling to reveal new interactions and structural insights into the mitochondrial respiratory chain of Trypanosoma brucei.

The paper identifies that OXPHOS-deficient cells sequester polyunsaturated fatty acids into triacylglycerols to protect against ferroptosis, observed in patient fibroblasts and hypoxia conditions.

The paper identifies recurrent mtDNA variants, particularly in the LSP2 promoter, as a cause of tubulointerstitial kidney disease in families with maternal inheritance.

The paper investigates the role of COX6B1 in cytochrome c oxidase assembly, finding it essential for both early redox-sensitive steps and late stabilization of the complex.

The paper investigates how mitochondrial rRNA sequence variation contributes to insulin resistance and metabolic syndrome in rats fed a high-fat diet.