Author

Craig A. Cummings

GenentechORCID 0000-0001-7276-9474Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:benchmarking· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alexander Spyridon BarasiD· 1 shared John-William SidhomiD· 1 shared Jordan AnayaiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Alexander Spyridon BarasORCID

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1 paper

Recent·Most cited

BioinformaticsCancer Research CommunicationsPeer-reviewedFeb 24, 2023

Probabilistic mixture models improve calibration of panel-derived tumor mutational burden in the context of both tumor-normal and tumor-only sequencing

Jordan Anaya, John-William Sidhom, Craig A. Cummings, Alexander Spyridon Baras

This paper introduces probabilistic mixture models to calibrate panel-derived tumor mutational burden (TMB) to exomic TMB, showing improved accuracy over linear regression.

6 citations

humanwhole-exome sequencing

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