Single-cell multiomics reveals archetypal regulatory programs shared across CD4 and CD8 T cell subsets in viral infection
Sarah K. Walker, Joris van der Veeken, Alexander Yu Rudensky, Yuri Pritykin
Author
Research Institute of Molecular PathologyORCID 0000-0001-7299-2174Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Sarah K. Walker, Joris van der Veeken, Alexander Yu Rudensky, Yuri Pritykin
Maria Avdeeva, Sarah K. Walker, Joris van der Veeken…·Yuri Pritykin
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This paper develops caffeine-responsive switches for CAR T cells, showing they can be controlled by caffeine and effectively clear tumors in mice.
Yuri Pritykin, Joris van der Veeken, Allison R. Pine…·Christina S. Leslie
The paper defines a shared differentiation trajectory of CD8 T cell dysfunction across cancer and infection using ATAC-seq and RNA-seq data from multiple studies.