Author

Ganesh babu Manoharan

University of LuxembourgORCID 0000-0001-7305-9845Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Daniel Kwaku AbankwaiD· 3 shared Karolina PaviciD· 2 shared Alejandro Yeste-VázqueziD· 1 shared Anthoula GaigneauxiD· 1 shared Candy Laura SteffeniD· 1 shared Carla Jane DuvaliD· 1 shared Christina Laurini· 1 shared Enrico GlaabiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

Daniel Kwaku AbankwaORCID

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3 papers

Recent·Most cited

BiochemistryiSciencePeer-reviewedNov 8, 2025

Proteomics- and BRET-screens identify SPRY2 as Ras effector that impacts its membrane organisation

Karolina Pavic, Fiona E. Hood, Carla Jane Duval…·Daniel Abankwa

The paper identifies SPRY2 as a novel K-Ras effector that impacts its membrane organisation through proteomics and BRET screens.

1 citation

proteomicsexperimental assay

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BiochemistrybioRxivPreprintSep 7, 2023

Identification of an H-Ras nanocluster disrupting peptide

Ganesh babu Manoharan, Candy Laura Steffen, Karolina Pavic…·Daniel Kwaku Abankwa

The paper identifies a peptide that disrupts the interaction between Gal1 and B-Raf-RBD, reducing H-Ras nanoclustering and MAPK signaling in cancer cells.

DOI 10.1101/2023.09.07.556635

humanproteomics

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BioinformaticsJournal of Chemical Information and ModelingPeer-reviewedAug 4, 2021

A Pharmacophore Model for SARS-CoV-2 3CLpro Small Molecule Inhibitors and in Vitro Experimental Validation of Computationally Screened Inhibitors

Enrico Glaab, Ganesh babu Manoharan, Daniel Abankwa

The paper develops a pharmacophore model for SARS-CoV-2 3CLpro inhibitors and validates computationally screened compounds experimentally.

46 citationstop 4%

machine learning (classical)drug response / drug discovery

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