Amanda L. Tapia

This study identifies 557 new gene-trait associations for hematological traits using transcriptome-wide association analysis in UK Biobank data.

MRLocus estimates gene-to-trait mediation effects using Bayesian methods on eQTL and GWAS data, showing high accuracy and better uncertainty estimation in simulations and real applications.

This paper performs a large-scale TWAS of blood cell phenotypes, identifies 239 gene-trait associations, and develops an R Shiny app to visualize TWAS results.

This study uses TOPMed whole genome sequences to improve imputation quality and detect rare variant associations in admixed African and Hispanic/Latino populations, identifying two novel associations with hematological traits.