Author

James J. Mulé

Moffitt Cancer CenterORCID 0000-0001-7354-0516Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Anders E. BerglundiD· 2 shared Douglas C. MarchioniD· 2 shared Jodi A. Balasi· 2 shared Jonathan V. NguyeniD· 2 shared Sean YoderiD· 2 shared Alex C. SoupiriD· 1 shared Andrew T. SmithiD· 1 shared Anthony E. Alleyne· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Anders E. BerglundORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 18, 2026

Spatially resolved multimodal hallmarks of response to neoadjuvant immunotherapies in the melanoma ecosystem in 2D and 3D

Zichao Liu, Xiaofei Song, Wei-Shen Chen…·Pei-Ling Chen

The paper analyzes the spatial molecular architecture of melanoma tumors under different immunotherapy regimens and identifies biomarkers predicting response to treatment.

DOI 10.64898/2026.09.12.751186

humanspatial transcriptomics

𝕏 PostBluesky

GenomicsCancer Research CommunicationsPeer-reviewedFeb 11, 2025

Evaluating the Radiation Sensitivity Index and 12-chemokine gene expression signature for clinical use in a CLIA laboratory

Anders Berglund, John Puskas, Sean Yoder…·Steven A. Eschrich

The paper evaluates the reproducibility and clinical applicability of two gene expression signatures under CLIA laboratory standards.

3 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

Cancer BiologyGenome biologyPeer-reviewedDec 5, 2024

Increased spatial coupling of integrin and collagen IV in the immunoresistant clear cell renal cell carcinoma tumor microenvironment

Alex C. Soupir, Mitchell T. Hayes, Taylor C. Peak…·Brandon J. Manley

The paper uses spatial transcriptomics to identify increased spatial coupling of integrin and collagen IV in immunoresistant clear cell renal cell carcinoma tumors, suggesting integrin as a therapeutic target.

30 citationstop 3%

humanspatial transcriptomics

𝕏 PostBluesky