Arnaud Échard

This study shows dimeric Alix nucleates CHMP4 polymerization, essential for ESCRT-III membrane remodeling, and demonstrates that dimerization is required for plasma membrane repair.

The paper introduces SiR-XActin, a far-red fluorescent probe for imaging actin dynamics in live cells with minimal cytotoxicity and without genetic modifications.

This study identifies CARM1-mediated methylation of ALIX as critical for its interactions with SH3-domain proteins during cytokinesis.

Cut-Detector automates the analysis of cytokinesis timing from time-lapse microscopy movies by detecting microtubule cuts in intercellular bridges.

This study shows that HIV-1 budding requires MICAL1-mediated actin disassembly at the plasma membrane, with Rab35 also playing a role in this process.

This study shows that F-actin, via Cofilin-1 and Arp2/3, promotes microtubule severing during cytokinetic abscission, independent of membrane scission.