NeurosciencebioRxivPreprint
TSC1 loss-of-function increases risk for tauopathy by inducing tau acetylation and preventing autophagy-mediated tau clearance
Carolina Alquézar, Kathleen M. Schoch, Ethan G. Geier…·Aimee W. Kao
This study identifies TSC1 loss-of-function as a risk factor for tauopathies by promoting tau acetylation and impairing autophagy-mediated tau clearance.
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