Author

Matthew T. Brewer

Iowa State UniversityORCID 0000-0001-7538-1934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan Patrick RobertsoniD· 1 shared Jeba R. J. Jesudoss ChelladuraiiD· 1 shared P. D. E. WilliamsiD· 1 shared Raffi V. AroianiD· 1 shared Richard J. MartiniD· 1 shared Theresa A. QuintanaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alan Patrick RobertsonORCID

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2 papers

Recent·Most cited

Molecular BiologyInternational Journal for Parasitology Drugs and Drug ResistancePeer-reviewedSep 23, 2025

Transcriptional responses to in vitro macrocyclic lactone exposure in Toxocara canis larvae using RNA-seq

Theresa A. Quintana, Matthew T. Brewer, Jeba R. J. Jesudoss Chelladurai

This study uses RNA-seq to analyze transcriptional changes in Toxocara canis larvae exposed to macrocyclic lactones, identifying differentially expressed genes and their biological implications.

DOI 10.1016/j.ijpddr.2025.100614

bulk RNA-seqstatistical model

𝕏 PostBluesky

Pharmacology & ToxicologyPLoS PathogensPeer-reviewedMay 17, 2024

The nematode (Ascaris suum) intestine is a location of synergistic anthelmintic effects of Cry5B and levamisole

P. D. E. Williams, Matthew T. Brewer, Raffi V. Aroian…·Richard J. Martin

This study investigates the synergistic effects of Cry5B and levamisole on nematode enterocytes, showing that levamisole accelerates and enhances Cry5B-induced Ca2+ influx and cell death.

3 citations

imagingmicroscopy & imaging analysis

𝕏 PostBluesky