Author

Cullen Demakis

University of WashingtonORCID 0000-0001-7553-1437Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Abbas IdrisiD· 1 shared Adam J. BroermaniD· 1 shared Andrew J. BorstiD· 1 shared Annika PhilominiD· 1 shared Arvind S. PillaiiD· 1 shared Connor WeidleiD· 1 shared David A. BakeriD· 1 shared Florian PraetoriusiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Abbas IdrisORCID

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1 paper

Recent·Most cited

BiochemistryNaturePeer-reviewedAug 14, 2024

De novo design of allosterically switchable protein assemblies

Arvind S. Pillai, Abbas Idris, Annika Philomin…·David A. Baker

This paper designs allosterically switchable protein assemblies using rigid-body coupling of effector-switchable modules, demonstrating cooperative ligand binding and structural changes similar to natural systems.

110 citationstop 1%

protein structuredeep learning

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