Author
University of California, Los AngelesORCID 0000-0001-7613-1953Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Liisa Lutter, David M. Beal, Maria Stanley…·Wei‐Feng Xue
This paper develops a method to perform three-dimensional single-particle reconstruction using AFM for rapid structural validation of proteins, demonstrated on SARS-CoV-2 Spike protein.
Liam D. Aubrey, Liisa Lutter, Kate Fennell…·Wei‐Feng Xue
The paper uses atomic force microscopy and cryo-electron microscopy to analyze Aβ42 fibril structures in vitro, identifying rare polymorphs similar to those found in human brain amyloid.
Irene Farinas, Youssra K. Al‐Hilaly, Liisa Lutter…·Louise C. Serpell
This paper investigates the structure of amyloid fibrils formed by the human tau-derived hexapeptide VQIVYK, revealing a polymorphous population with a twisted protofilament architecture.
Ke Hou, Peng Ge, Michael R. Sawaya…·David S Eisenberg
The paper shows a D-peptide disassembles AD-tau fibrils via a strain-relief mechanism involving oppositely twisted fibrils.