Author
Amsterdam UMC Location University of AmsterdamORCID 0000-0001-7689-3042Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Niels Meijns, Gema Muñoz González, Sabine Stolker…·Antonio Luchicchi
This study uses human post-mortem brain slice cultures to investigate focal and subtle myelin damage in multiple sclerosis, showing the model's utility for studying human myelin pathology.
Dennis Serge Metselaar, Michaël Hananja Meel, Joshua R. Goulding…·Esther Hulleman
This study shows gemcitabine selectively kills ATRT by degrading SIRT1, activating p53 and SHH signaling, and significantly improves survival in xenograft models.
Eelke Brouwers, Marjolein Breur, Maria Susana Jorge…·Rogier Min
This study investigates whether seizures exacerbate myelin vacuolization and astrocyte swelling in a mouse model of MLC, finding no significant acute worsening of these features.
Stephanie Dooves, Liza Martha Linda Kok, Dwayne B. Holmes…·Vivi Majella Heine
This study investigates how 4H leukodystrophy mutations affect cortical interneuron development using induced pluripotent stem cells and finds reduced GABAergic synapses and altered interneuron markers.
Ingrid H.C.H.M. Philippens, Kinga P. Böszörményi, Jacqueline A. M. Wubben…·Ernst J. Verschoor
This study shows SARS-CoV-2 infection in macaques leads to brain inflammation and Lewy body formation, suggesting potential long-term neurological effects.