Author
University of PittsburghORCID 0000-0001-7693-5863Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Li Wan, Xiaochen Li, Paul Vittot…·Yuan Chang
This study shows that MCV small T protein recruits HSP70 to facilitate LT helicase remodeling and DNA unwinding, revealing a conserved mechanism for replication complex assembly.
Yijen Lin Wu, Anthony Christodoulou, Jan Hendrik Beumer…·Joel S. Greenberger
Maternal administration of mitochondrial-targeted JP4-039 mitigates fetal brain injury and preserves mitochondrial function after mid-gestation radiation exposure.
Edward Chuang, Ryan R. Cupo, Jeffrey R. Bevan…·James Shorter
The paper identifies a small-molecule stimulator of the human Hsp70-disaggregase system that selectively activates DnaJB1- or DnaJB4-containing chaperone complexes.
Mariarosaria De Rosa, Ryan P. Barnes, Prasanth R. Nyalapatla…·Patricia Lynn Opresko
The paper shows that OGG1 and MUTYH repair activities are required for telomeric 8-oxoguanine-induced cellular senescence, with their loss reducing senescence and telomere dysfunction.
Daniel Rand, Orly Ravid, Dana Atrakchi…·Itzik Cooper
This paper investigates how endothelial iron homeostasis affects BBB integrity through the HIF2α-Ve-cadherin pathway, identifying DFO and JP4-039 as potential therapeutic agents.