Author

Junfeng Shi

Hunan UniversityORCID 0000-0001-7705-8866Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Dingxiao ZhangiD· 2 shared Yuqing FengiD· 2 shared Zenghui LiiD· 2 shared Bin XuiD· 1 shared Cheng ZouiD· 1 shared Dan YuaniD· 1 shared Hao XuiD· 1 shared Hong Jin HaniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Dingxiao ZhangORCID

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2 papers

Recent·Most cited

Cancer BiologyCellular and Molecular Life SciencesPeer-reviewedOct 5, 2024

Stabilization of RRBP1 mRNA via an m6A-dependent manner in prostate cancer constitutes a therapeutic vulnerability amenable to small-peptide inhibition of METTL3

Yuqing Feng, Zenghui Li, Jinwei Zhu…·Dingxiao Zhang

This study identifies METTL3-mediated stabilization of RRBP1 mRNA via m6A in prostate cancer and develops small-peptide inhibitors to target this pathway.

12 citations

humanbulk RNA-seq

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BiochemistryAngewandte Chemie International EditionPeer-reviewedApr 12, 2024

A Stapled Peptide Inhibitor of METTL3-METTL14 for Cancer Therapy

Zenghui Li, Yuqing Feng, Hong Jin Han…·Junfeng Shi

This paper develops a stapled peptide inhibitor of METTL3-METTL14 that suppresses tumor growth by inhibiting m6A methylation and promoting METTL3 degradation.

65 citationstop 1%

humanproteomics

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