Iulia M. Lazar

XMAn Update expands a database of mutated peptides by integrating cancer-related variants from COSMIC and CGC datasets to improve variant detection in mass spectrometry analyses.

This paper develops a scaffold-free 3D in vitro model to study metastatic cancer cell behavior in the brain tumor microenvironment, showing it mimics key interactions and is effective for drug testing.

This study uses proteomic analysis to evaluate the response of HER2+ breast cancer cells to Lapatinib and Ipatasertib, identifying proteins and pathways affected by these drugs.

This study investigates how HER2+ breast cancer cells respond to brain cell-secreted factors, finding that exposure leads to quiescence and altered cellular processes.