Ronald I. Swanstrom

This study identifies HIV-1-induced SUMOylation of host RNA splicing factors, mediated by Vif, which regulates viral RNA splicing and infectivity.

The paper studies cotranslational folding and autoproteolytic processing of HIV-1 protease during viral particle assembly.

This study investigates how HIV-1 Nef's ability to downregulate MHC-I affects the size of the replication-competent viral reservoir in South African women on ART, finding a significant association between MHC-I downregulation and reservoir size.

This study examines HIV-1 mutants that produce only one transcription start site RNA and finds that they display complementary replication functions restored by reversion.

The paper identifies that HIV-1 rebound virus primarily originates from a small number of lineages that entered the reservoir near ART initiation, despite the reservoir containing older sequences.

The paper measures CSF proteins in HIV-1 infected and uninfected individuals, identifying patterns of protein changes associated with CNS injury and treatment effects.

This paper shows that m6A methylation regulates HIV-1 RNA stability and alternative splicing through YTHDC1 and YTHDF2.