Author

Jacob H. Steele

University of HoustonORCID 0000-0001-7782-6677Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Yuhong WangiD· 2 shared Jordan JohnsoniD· 1 shared Miriam Gavriliuc· 1 shared Ran Lin· 1 shared Shoujun XuiD· 1 shared Victor G. StepanoviD· 1 shared Yanjun Chen· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

Yuhong WangORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 24, 2025

EF-G Mutations Reveal Correlation between Power Stroke and Translocation Fidelity in Protein Synthesis

Yanjun Chen, Jacob H. Steele, Shoujun Xu, Yuhong Wang

This study measures EF-G power stroke and its effect on ribosome translocation fidelity using quantum sensing, showing that mutations alter translocation steps and fidelity.

DOI 10.1101/2025.06.24.661293

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

BiophysicsThe International Journal of Biochemistry & Cell BiologyPeer-reviewedApr 8, 2025

Multi-Channel smFRET study reveals a Compact conformation of EF-G on the Ribosome

Jordan Johnson, Jacob H. Steele, Ran Lin…·Yuhong Wang

This study uses multi-channel smFRET to show that EF-G adopts a compact conformation with specific mutations, impacting translocation and Poly(Phe) synthesis.

5 citations

E. colifluorescence / live-cell microscopy

𝕏 PostBluesky