Author

Jean-Michel Carter

Nanyang Technological UniversityORCID 0000-0001-7932-2368Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Kamalakshi DekaiD· 2 shared Yinghui LiiD· 2 shared Benita Kiat Tee TaniD· 1 shared Daniel Aron AngiD· 1 shared Jianbiao ZhouiD· 1 shared Joel Heng Loong TaniD· 1 shared Kayla M. Borland· 1 shared Matthias HeißiD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

Kamalakshi DekaORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJul 5, 2024

TWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in Triple-Negative Breast Cancer

Nicholas Sim, Jean-Michel Carter, Kamalakshi Deka…·Yinghui Li

This study shows that TWEAK/Fn14 signalling rewires the transcriptomic and epigenomic landscape of TNBC, promoting metastasis through super-enhancer-driven metabolic reprogramming.

37 citationstop 3%

humanbulk RNA-seq

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Cancer BiologyNature CommunicationsPeer-reviewedMar 21, 2024

Aberrant non-canonical NF-kappaB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma

Daniel Aron Ang, Jean-Michel Carter, Kamalakshi Deka…·Yinghui Li

This study shows that aberrant non-canonical NF-kappaB signalling reprograms the epigenome to drive oncogenic transcriptomes in multiple myeloma by promoting super-enhancers and cis-regulatory interactions.

19 citationstop 3%

humanDNA methylation

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Molecular BiologyNucleic Acids ResearchPeer-reviewedNov 24, 2020

Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6

Tommaso Selmi, Shobbir Hussain, Sabine Dietmann…·Michaela Frye

The paper identifies NSUN6 as a methyltransferase that specifically targets mRNA 3UTR regions with the CTCCA motif, affecting translation termination but not essential for mouse development.

200 citationstop 1%

humanbulk RNA-seq

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