Author

Rene Yu-Hong Cheng

University of WashingtonORCID 0000-0001-7946-100XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:non-human primate· 1

Frequent Co-Authors

Richard G. JamesiD· 3 shared David J. RawlingsiD· 2 shared Andee R. OttiD· 1 shared Andrew T. McGuireiD· 1 shared Anna E Helmers· 1 shared Chris Thouvenel· 1 shared Christina LopeziD· 1 shared Claire M. Stoffers· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioengineering

Richard G. JamesORCID

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3 papers

Recent·Most cited

Molecular BiologyMolecular Therapy AdvancesPeer-reviewedJan 9, 2026

Humanized mice enable in vivo evaluation of engineered plasma cell biology and therapeutic function

Tyler F. Hill, Anna E Helmers, Rene Yu-Hong Cheng…·Richard G. James

This study develops a humanized mouse model to evaluate engineered plasma cells and their therapeutic antibody secretion, showing long-term antibody production and neutralization of SARS-CoV-2.

2 citationstop 4%

humanexperimental assay

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BioengineeringNature ProtocolsPeer-reviewedFeb 20, 2025

Linking single-cell transcriptomes with secretion using secretion-encoded single-cell sequencing (SEC-seq)

Justin Langerman, Sevana Baghdasarian, Rene Yu-Hong Cheng…·Dino Di Carlo

SEC-seq links single-cell transcriptomes with secretion levels by isolating cells and secretions in Nanovials, enabling analysis of secretory phenotypes and their genetic drivers.

22 citationstop 3%

humanscRNA-seq

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BioengineeringbioRxivPreprintOct 29, 2023

Advancing Cell Therapies: Single-Cell Profiling, Generation, Expansion, and Gene Delivery in Rhesus Macaque Plasma B Cells

Rene Yu-Hong Cheng, Shannon A. Kreuser, Noelle Dahl…·Richard G. James

This study expands NHP B cells ex vivo, identifies unique plasma cell markers, and establishes AAV transduction conditions for engineered B cell therapies.

2 citations

non-human primatescRNA-seq

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