Cancer BiologybioRxiv
Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2
Weini Wang, Yanchi Zhou, Ji Wang…·Kenneth P. Nephew
This study shows that inhibiting HOTAIR and EZH2 reduces ovarian cancer stem cell resistance to platinum chemotherapy and improves survival in vivo.
DOI 10.1158/1535-7163.mct-23-0314