Marcin Grabowicz

The paper identifies critical charge-based interactions between LolA and LolB proteins in lipoprotein trafficking by screening mutations in LolB and showing that charge reversals in LolA can suppress lethality.

The paper investigates phage resistance in E. coli due to O-antigen expression and finds that most E. coli in the gut are resistant, limiting phage impact on bacterial composition.

This study shows that longer O-antigen polysaccharides on LPS in E. coli and Shigella flexneri weaken the outer membrane barrier, increasing antibiotic susceptibility.

The paper challenges a bipartite model of LolC-LolA interaction by showing the Hook is essential while the Pad is ancillary in lipoprotein trafficking in E. coli.