Author

Chee Leng Lee

Monash UniversityORCID 0000-0001-8036-459XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:protein sequence· 1

Frequent Co-Authors

Colin William PoutoniD· 3 shared Rekha Shandre MuganiD· 3 shared Stewart A. FabbiD· 3 shared Asuka TakanashiiD· 2 shared Marc PellegriniiD· 2 shared Adam ThomasiD· 1 shared Bailey E. WilliamsiD· 1 shared Benjamin J. BroomfieldiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

Colin William PoutonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologyFrontiers in ImmunologyPeer-reviewedSep 16, 2026

Targeting a malaria merozoite surface protein with mRNA vaccine generates multifunctional antibodies

Adam Thomas, Tom Runz, Timothy K.C. Ho…·James G. Beeson

This study evaluates mRNA vaccines encoding PfMSP2, showing they induce strong IgG responses and functional antibodies against malaria merozoites, comparable to or better than a protein-based vaccine.

1 citationtop 3%

mouseprotein sequence

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ImmunologyThe Journal of Experimental MedicinePeer-reviewedFeb 5, 2025

Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection

Benjamin J. Broomfield, Chin Wee Tan, Raymond Z. Qin…·Joanna R. Groom

This paper shows that temporarily blocking type I interferon during viral infection boosts CD8+ T cell memory and vaccine effectiveness by promoting TSCM cell formation.

42 citationstop 1%

mousebulk RNA-seq

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ImmunologyMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewedNov 15, 2024

mRNA vaccines encoding membrane-anchored receptor-binding domains of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting

Hareth A. Al-Wassiti, Stewart A. Fabb, Samantha L. Grimley…·Colin William Pouton

8 citations

mouseexperimental assay

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