Sook Wah Yee

This study uses proteomic profiling to identify age-related changes in transporter proteins in human brain microvessels, revealing alterations in BBB permeability and drug disposition.

This study identifies FLVCR2 as the primary choline transporter at the blood-brain barrier, determines its structures, and elucidates its mechanism of choline uptake.

Rosace improves analysis of deep mutational scanning data by using Bayesian shrinkage and position information, outperforming existing methods in simulations and real data.

GenEpi detects gene-based epistasis using machine learning, outperforming existing methods on simulated data and identifying disease-related variants in Alzheimer's disease.