Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids
Valentin Bonnet, Erik Maikranz, Marianne Madec…·Charles Naim Baroud
This study uses a cancer-on-a-chip model to show that APC mutations impair T cell engagement and killing of tumor spheroids, despite normal migration and accumulation.