Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewed
Spatial molecular profiling of mixed invasive ductal-lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations
Osama Shiraz Shah, Azadeh Nasrazadani, Julia Foldi…·Steffi Oesterreich
This study uses spatial molecular profiling to show that mixed invasive ductal-lobular breast cancers have distinct molecular subtypes, oncogenic signatures, and mutations in different tumor regions, leading to prognostic uncertainty and therapeutic challenges.
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