Author

Seemon Coomar

University of BaselORCID 0000-0001-8206-403XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dennis G. GillinghamiD· 2 shared Alexander V. PensoniD· 1 shared Juerg SchwalleriD· 1 shared Omar Ibrahim Abdel-WahabiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersMolecular Biology

Dennis G. GillinghamORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 1, 2021

Arylsulfonamide mediated RBM39 degradation causes aberrant splicing of mitotic kinesins

Seemon Coomar, Alexander V. Penson, Juerg Schwaller…·Dennis G. Gillingham

The paper identifies two mitotic kinesins aberrantly spliced due to RBM39 degradation by ArSulfs, linking this splicing change to antiproliferative effects.

1 citation

humanproteomics

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BiochemistrybioRxivPreprintFeb 8, 2019

Exploring DCAF15 for reprogrammable targeted protein degradation

Seemon Coomar, Dennis G. Gillingham

This study identifies an arylsulfonamide that can be chemically modified and demonstrates its behavior in reprogramming the CRL4DCAF15 E3 ligase to degrade RBM39.

DOI 10.1101/542506

humanexperimental assay

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