Poly ADP-ribosylation of SET8 leads to aberrant H4K20 methylation domains in mammalian cells
Pierre‐Olivier Estève, Sagnik Sen, Udayakumar S. Vishnu…·Sriharsa Pradhan
This study shows that PARP1 poly ADP-ribosylates SET8, impairing its function and leading to altered H4K20 methylation domains and chromatin states.